Lesson Code: BE0200

Professor in charge: Mylonis Ilias, Associate Professor

Other Teachers: G. Simos, P. Liakos, G. Hahami

ECTS: 5.00

Type|Type of Course: YP | BACKGROUND

Teaching Semester: 1st Semester

Hours per week: 5 Hours

Total Time (Teaching Hours + Student Workload) 135 Hours

Prerequisites: NO

Language of Instruction: Greek

Available for Erasmus: YES

Semester Lectures: Details/Lectures

Teaching Method: Face-to-face and specific: The teaching of the "Medicinal Chemistry" course consists of lectures, tutorials, seminars and laboratory exercises. Attendance at tutorials and laboratory exercises is mandatory. The lectures develop the material described above. In the tutorials, the theoretical background of the laboratory exercises, the theoretical basis and the applications of the techniques that are currently used in biomedical research and laboratory medicine are developed. In the seminars, the course material is analyzed in the form of questions and answers. The laboratory exercises aim to familiarize the students with the use of techniques and instruments to carry out an experimental / research work. After completing the laboratory exercises, the student must have acquired some general skills of experimental work, i.e. be able to: 1. plan and conduct an experiment, 2. receive and process experimental data, 3. judge the results and reveal possible experimental errors, 4. draw the conclusions, 5. handle the basic laboratory equipment – spectrophotometer, pH-meter, electrophoresis device, etc. 6. to know and observe laboratory safety rules, 7. to follow instructions, 8. to work in a team. Attendance is mandatory in all tutorials and laboratory exercises. • POWERPOINT: for preparing lecture material and viewing slides and videos. • E-class: • The study guide (explanatory material & additional bibliography), the theory and protocols of the laboratory exercises, the slides of the presentations after each lesson as well as videos and scientific articles related to the taught material are made available online to students through the e-class. • The evaluation of the course by the students is done online. • Communication with the students is done through the e-class platform or by e-mail • Laboratory exams are done online with the simultaneous use of the e-class and teams platform

Evaluation Method: The assessment language of the students is Greek.
The evaluation of the students' performance in the course is done:
1. with an evaluation of the results of each laboratory exercise presented in the form of a written assignment after each laboratory exercise.
2. by electronic means (e-class and MS Teams) for end-of-semester lab exams with multiple choice, true-false, matching, layout questions.
In the Laboratory exams, the material to be examined is the theory, methodology and methods of processing results included in the Laboratory Exercises Guide or developed by the teachers during the workshops and the corresponding tutorials.
3. with written examinations of the theory of the course "Medicinal Chemistry" in the examination period of the winter semester with free development, multiple choice, true-false and matching questions.
In the theory exams of the course, the material to be examined is the material of the lectures and tutorials according to the analytical material of the course.
4. Only those students who have passed the Laboratory exams have the right to participate in the course exams. The final grade of the course is formed by the contribution of the laboratory grade (20%) and theory (80%) with performance in theory 50% as a prerequisite.
All of the above can be accessed by the students as they are contained in the Course Guide that is distributed to all students in print, and is posted in the e-class.

Objective Objectives/Desired Results: The general purpose of the course "Medicinal Chemistry" is to introduce students to selected chapters of general, physical, organic and biological chemistry with the ultimate goal of forming a knowledge base and enabling them to design and analyze the application of chemical processes in the interpretation biomedical phenomena, the chemical structure and properties of basic biomolecules (carbohydrates, lipids, amino acids, proteins and enzymes) as well as the effect of environmental chemistry on human health. Furthermore, the course seeks to provide students with the basic elements necessary to understand and assimilate courses of subsequent semesters, such as Biochemistry, Physiology, Pharmacology, Clinical Biochemistry, and laboratory medicine chapters applied daily to diagnosis.
The specific objectives of the course are specialized in the following intended learning outcomes:

Upon successful completion of the course, the student will be able to:
He/she will be able to use the acquired knowledge in order to:
• be able to describe the chemical basis of biomedical phenomena, the structure, properties, roles and action of basic chemical elements and compounds of biological importance as well as the toxicity of xenobiotic substances, the structure, properties and roles of basic biomolecules such as carbohydrates, lipids, amino acids, proteins and enzymes, conducting laboratory analyzes and assessing the correctness of the results.
• to make use of the knowledge acquired in the course as a basis for understanding the courses of the longer semesters: Biochemistry, Physiology, Pharmacology, Clinical Biochemistry and Toxicology.
• have the ability to analyze data with a critical approach and be able to search and analyze information relevant to Medicinal Chemistry from various sources.
• use the basic equipment of a chemical laboratory and carry out basic chemical analyses.
• collaborate with fellow students in a laboratory environment to perform basic chemical analyzes and process their results.

General Skills
• Search, analysis and synthesis of data and information, using the necessary technologies
• Adaptation to new situations
• Decision making
• Autonomous work
• Teamwork
• Exercise criticism and self-criticism
• Promotion of free, creative and inductive thinking

Course URL :

Course Description:

Recommended reading: • Notes from deliveries – Posted in e-class.
• A. Tsakalov "Medicinal Chemistry in questions and answers" - posted for free on the KALLIPOS platform:
• Varvoglis A. G.: Epitomical organic chemistry, Ziti Publications.
• GA TAYLOR: Organic Chemistry for Medical and Biological Sciences.
• Raymond Chang: “Physical Chemistry for the Chemical and Biological Sciences”, University Science Books.
• Caret Robert L., Denniston Katherine J., Topping Joseph J.: "Principles & applications of inorganic, organic & biological chemistry" Paschalidis Publications.

Τμημα Ιατρικής - Πανεπιστήμιο Θεσσαλίας
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