Lectures: 28 in total (14 x 2 hours and 14 x 1 hour) held in auditorium format (whole-class), throughout the semester. Attendance is mandatory. Lectures are accompanied by discussion of cases and exercises on real clinical problems.

Face-to-face lectures

Lectures, Attendance is mandatory

PowerPoint presentations during lectures. Student communication via University of Thessaly’s Eclass platform.

Assessment Language: Greek

Assessment Method: Multiple-choice test

Passing Grade: 50%

Assessment criteria are clearly defined and will be presented to students on the first lecture of the semester.

The general aim of the course is to introduce students to the underlying mechanisms of various diseases (hematologic system, liver, gastrointestinal tract, pancreas, adrenal glands, hypothalamus-pituitary, thyroid-parathyroid, central and peripheral nervous system). It further aims to provide the foundational knowledge for understanding the clinical manifestations of these diseases based on the underlying pathophysiological disturbances, ultimately guiding appropriate therapeutic approaches.

Upon successful completion of the course, students will be able to:

– Systematically and rationally approach symptoms based on pathophysiological mechanisms.

– Organize patient history, clinical examination, and lab data to support a pathophysiologically justified diagnosis.

– Design basic diagnostic and therapeutic algorithms in accordance with the disease mechanisms.

– Use appropriate terminology and conceptual understanding to explain clinical phenomena and therapeutic decisions.

– Collaborate with peers to analyze clinical cases and suggest plausible pathophysiological interpretations.

General Abilities

– Research, analysis, and synthesis of data and information using necessary technologies

– Decision making

– Independent work

– Teamwork

– Interdisciplinary collaboration

– Critical thinking and self-reflection

– Promotion of free, creative, and inductive thinking

Section 1: Hematopoietic System

Hematopoiesis and hematopoietic factors, pathophysiology of anemias, platelet function physiology and pathophysiology of platelet disorders, concept of hypercoagulability and thrombophilia.

Section 2: Liver

Jaundice, acute and chronic hepatitis, cirrhosis – pathophysiology and complications.

Section 3: Gastrointestinal Disorders

Malabsorption, diarrheal syndromes, constipation, defecation disorders, inflammatory bowel diseases, esophageal motility disorders, gastric dysfunction/gastritis.

Section 4: Endocrine Disorders

Disorders of the pancreas, adrenal glands, hypothalamus, pituitary, parathyroids, and thyroid.

Section 5: Nervous System Disorders

Extrapyramidal syndromes, motor neuron disease, neuromuscular junction disorders, stroke, dementia, demyelinating diseases.

1. Moutsopoulos – Principles of Pathophysiology, Athanasios Tzioufas / Panagiotis Vlachoyiannopoulos, 1st ed. 2018, Publisher: Broken Hill Publishers Ltd

2. Pathological Physiology, Collective Work / Eds. Pandelis Zembekakis, Maria Papaioannou, 3rd ed., 2024, Publisher: University Studio Press

3. Related articles from reputable international medical journals