Α. Vasilaki, Ε. Asprodini, P. Kotsi, K. Mantzarlis, A. Manolakis, I. Stefanidis, G. Leontaritis

Face to Face/distance learning.

Teaching of Pharmacology II consists of lectures and seminars/tutorials. Attendance of Seminars is compulsory.

MANDATORY ATTENDANCES -LECTURES Workshops

Information and Communication Technologies are used for the preparation of the lecture material, the online information and provision of supplementary learning material to students.

Specifically:

• Common software (e.g., MS powerpoint) is used to prepare lecture material and display slides and videos.
• The study guide (detailed supplementary material & additional bibliography), the tutorial material (clinical cases), the theory and protocols of the laboratory exercises, the slides of each lecture as well as relevant videos and scientific articles made available electronically and online to students through the e-class system of our university.
• Common software (e.g., MS excel) is used to statistically process student assessment.

Announcements, information etc are available online via e-class. Communication is also done via e-mail.

The language of assessment is Greek/ English for ERASMUS.

 Evaluation methods.

-A final written test

-Multiple-choice test 

Final Grade:

The final grade of the course is the grade of the written exams.

Aims of the course

The objective of this course, which is a continuation of BASIC AND CLINICAL PHARMACOLOGY: INTRODUCTION-NEURAL SYSTEM, is for the student to become familiar with and learn: basic groups of drugs, their mechanisms of action, their indications and contraindications, their interactions, their basic side effects, and the mechanisms leading to them. The student will be exposed to and learn about drugs related to diseases of other systems of the human body and the field of chemotherapy. As part of the students’ immersion in the field of chemotherapy, several relevant workshops are also held. The purpose of the laboratory rotations is to expose students to research, particularly the translational research required for drug discovery and development. By attending and successfully completing this course, the student will have a very good understanding of pharmacology and its role in clinical practice.

Upon successful completion of the course, the students will be able to

– Understand the mechanisms of action of the major drug classes,

– Have knowledge of the major classes of drugs

– To distinguish their indications and contra-indications, their interactions, their main adverse effects, and the mechanisms leading to them.

– Use their knowledge to make decisions about the correct choice of drugs

– Analyze the mechanisms that lead to adverse reactions

– Understand the process of drug discovery and development

– Become familiar with and learn the fundamentals of translational research necessary for drug discovery and development

General Abilities

The course aims to develop the following general competencies in students:

• Search for, analyze and synthesize data and information using the necessary technologies.
• Adapting to new situations.
• Working independently.
• Working in groups.
• Working in an interdisciplinary environment.
• Criticism and self-criticism.
• Generating new research ideas.
• Respect for diversity and complexity.
• Respect for the natural environment.
• Demonstrate social, professional, and ethical responsibility regarding gender issues.
• Encourage free, creative, and deductive thinking

Theoretical clinical skills

[1] Introduction

[2] Hormones of the Hypothalamus & Pituitary 

[3] Thyroid and antithyroid drugs

[4] Adrenocorticosteroids & Adrenocorticoid Antagonists

[5] Factors Affecting Bone Homeostasis                     

[6] Gonadal Hormones & Thyroid Inhibitors

[7] Gonadal Hormones & Male Inhibitors

[8] Antihypertensive drugs               

[9] Vasoactive peptides         

[10] Diuretic drugs

[11] Vasodilators & treatment of angina

[12] Drugs used in the treatment of heart failure.

[13] Drugs used in cardiac arrhythmias.

[14] Drugs used in the treatment of gastrointestinal diseases.

[15] Drugs used in the treatment of dyslipidemia.

[16] Drugs to treat Anaemia; haematopoietic factors

[17] Drugs for Blood Coagulation Disorders.        

[18] Respiratory drugs                   

[19] Antidiabetic Drugs & Drugs for Obesity

[20] Clinical Applications of Antidiabetic Drugs SEMINAR

[21] Antibiotics

[22] Antiviral Drugs

[23] Antimycobacterial drugs

[24] Antifungal Drugs

[25] Clinical applications of antibiotics SEMINAR

[26] Antiprotozoal drugs

[27] Anthelmintic drugs

[28] Anticancer Drugs

[29] Targeted therapeutic approaches

[30] Clinical applications of anti-cancer drugs SEMINAR

[31] Immunopharmacology

[32] Medicines in Pregnancy SEMINAR

[33] Drugs and Nanomedicine SEMINAR

[34] Refreshing lectures 

Workshops

(1) Drug Discovery and Development – Preclinical & Clinical Evaluation of New Drugs

(2) Developmental therapeutics program, NCI/NIH, USA

(3) Animal models of human diseases in drug discovery and development.

• – Basic and Clinical Pharmacology 2nd edition ISBN 9789925576159 (Eudoxos 94643689)
• – Pharmacology, 8th edition ISBN 9789605831738 (Eudoxos 59395656)
• – Pharmacology ISBN 9789605837310 (Eudoxos 122087214)
• – https://dtp.cancer.gov/
• – Web/other resources/pubmed/reviews (Related journals: Nature drug discovery, Drugs today, European journal of pharmacology, Pharmacology & Therapeutics, Journal of experimental pharmacology, Molecular pharmacology, Biochemical pharmacology etc)