AUTOIMMUNE DISEASES

AUTOIMMUNE DISEASES

AUTOIMMUNE DISEASES

Lesson Code: PTH1400

Professor in charge: Bogdanos Dimitrios, Professor

Other Teachers: CHRISTINA G. KATSIARI

ECTS: 2.00

Type|Type of Course: OP | SCIENTIFIC AREA

Teaching Semester: 14th Semester

Hours per week: 2 hours

Total Time (Teaching Hours + Student Workload) 54 Hours

Prerequisites: NO

Language of Instruction: GREEK

Available for Erasmus: NO

Semester Lectures: Coming Soon…

Teaching Method: LECTURES Power point

Evaluation Method:

Written exams (20 multiple-choice questions, no negative marking, 10 of which must be answered within 60 minutes) General assessment criteria are discussed during the introductory course..


Objective Objectives/Desired Results: The general purpose of the course is to introduce students to the basic knowledge of autoimmune diseases and to enable them to design, analyze and write papers. Furthermore, the course seeks to provide students with the essentials for applied knowledge of clinical immunology. The specific objectives of the course are specialized in the following intended learning outcomes:

Upon successful completion of the course, the student will be able to:

He/she will be able to use the acquired knowledge in order to:

  • to draw complex schemes of pathophysiological mechanisms
  • to write papers individually or in collaboration with other members (students, EDIP, faculty)
  • to use literature search tools
  • be equipped to pursue future careers in specialties involving basic and applied knowledge of clinical immunology
  • to organize thinking about understanding immune signaling and immunity
  • to approach diseases characterized by immune disorders with structural thinking
  • to collaborate with fellow students to produce research work

Course URL : www.autorheumatology.com

Course Description: 1. Introduction to Immunology and Autoimmunity
2. Epidemiology of autoimmune diseases: Why are they increasing?
3. Genetic, Epigenetic and Environmental Mechanisms of Autoimmunity Induction
4. Autoreactive immune responses, inflammatory and regulatory lymphocytes with examples
5. Autoantigens/Autoantibodies: Diagnostic and clinical significance, new and classic measurement methods
6. Autoantigens – Autoantibodies
7. Diagnostic and clinical criteria of Autoimmune Diseases – Practical applications and Diagnostic Algorithms
8. Liver / Skin / CNS / Lungs / Gastrointestinal system and Autoimmune Diseases with examples
9. Non-Organ Specific Autoimmune Diseases/Pathogenesis, Clinical Practice - Therapeutic Options
10. Organ-Specific Autoimmune Diseases/ Pathogenesis, Clinical Practice - Therapeutic Options
11. Experimental Models of Autoimmune Diseases
12. Treatments - Immunosuppressive drugs. Steroids- Action, Clinical Applications, Side Effects
13. Treatments - Immunosuppressive drugs. Disease Immunomodulators/ Action, Clinical Applications, Side Effects
14. Treatments - Immunosuppressive drugs. Monoclonal Antibodies and Other Biological Therapies Immunomodulating Disease/ Action, Clinical Applications, Side Effects

Recommended reading:
  1. Teachers' Notes
  2. Clinical Immunology, Papakosta Despina, Garifallos Alexandros and colleagues,
  3. Basic principles and clinical approach, Boura Panagiota and Associates
  4. Carlo Perricone, Yehuda Shoenfeld , Mosaic of Autoimmunity, The Novel Factors of Autoimmune Diseases Revisited, , Elsevier 2019

Periodically

  1. Journal of Autoimmunity,
  2. Autoimmunity Reviews
  3. Clinical Immunology
  4. Nature Immunology,
  5. New England Medical Journal
  6. Lancet
  7. Mediterranean Journal of Rheumatology
  8. Annals of Rheumatic Diseases
  9. Arthritis and Rheumatology
  10. Nature Reviews of Rheumatology

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