Information and Communication Technologies are used for the preparation of the lecture material, the online information and provision of supplementary learning material to students. Specifically: • Common software (e.g., MS powerpoint) is used to prepare lecture material and display slides and videos. • The study guide (detailed supplementary material & additional bibliography), the tutorial material (clinical cases), the theory and protocols of the laboratory exercises, the slides of each lecture as well as relevant videos and scientific articles made available electronically and online to students through the e-class system of our university. • Common software (e.g., MS excel) is used to statistically process student assessment. Announcements, information etc are available online via e-class. Communication is also done via e-mail.
STUDENT EVALUATION
-The language of evaluation is Greek – Participation 20%, -Workshops by students 80%
Objective Objectives/Desired Results:
The course is designed to complement the knowledge acquired by medical students in Pharmacology I and II by focusing on specific pharmacological topics, new pharmacological approaches and applications largely related to molecular pharmacology. Adopting a drug target-based approach rather than the traditional organ/system-based approach, the course explores contemporary developments and the research trend towards the development of new drugs and therapeutic approaches based on the molecular environment of cells, arising from the modern detailed understanding of cellular processes and chemical responses of cells and, by extension, the body. During the course, the student will be introduced to specific pharmacological approaches and tools where he/she will deepen his/her knowledge through active and interactive participation in the development of projects on contemporary issues and applications arising from the continuous dynamic development of the science of pharmacology.
Upon successful completion of the course, the student will be familiar with •Innovative new therapeutic approaches -their applications -their mechanisms of action -their adverse effects • Special topics in pharmacology such as pharmacogenomics, precision medicine, vaccines. • Issues related to drug use and modern society. • With modern tools to support medical decision-making and the correct and safe use of drugs
General Abilities The course aims to develop the following general competencies in students: • Search for, analyze and synthesize data and information using the necessary technologies. • Adapting to new situations. • Working independently. • Working in groups. • Working in an interdisciplinary environment. • Criticism and self-criticism. • Generating new research ideas. • Respect for diversity and complexity. • Respect for the natural environment. • Demonstrate social, professional, and ethical responsibility regarding gender issues. • Encourage free, creative, and deductive thinking.
Course URL :
https://eclass.uth.gr/courses/MED_U_188/
Course Description:
Indicative topics for discussion/study 1. New small molecule therapeutics 2. Biological agents as drugs – Therapeutic monoclonal antibodies – Cytokines 3. Special Chapters in Pharmacology – Pharmacogenomics – Precision Medicine – Nanotechnology and pharmaceuticals – Vaccines – Common Terminology Criteria for Adverse Events Version 5.0 (CTCAE 5.0) – Pharmacological databases (WHO list of essential medicines, Drugbank, DIC tools, etc.) 4. Drugs of natural origin 5. Modern lifestyle and drugs – drugs in sports
Recommended reading:
• ΜΟΡΙΑΚΗ ΦΑΡΜΑΚΟΛΟΓΙΑ. ΠΑΠΑΔΗΜΗΤΡΙΟΥ ΕΥΑΓΓΕΛΙΑ. Εκδόσεις ΠΑΡΙΣΙΑΝΟΥ Α.Ε. Δεκ 2010. ISBN 9789603946090. Κωδικός Βιβλίου στον Εύδοξο: 41774 • Molecular Pharmacology: From DNA to Drug Discovery. Author(s): Dickenson J etal. 2013 John Wiley & Sons, Ltd. Online ISBN:9781118451908. Κωδικός Βιβλίου στον Εύδοξο: 80500512 • Web/other resources/pubmed/reviews