EMBRYOLOGY PRINCIPLES OF THE EVOLUTION OF CONGENITAL DISORDERS BY SYSTEM

EMBRYOLOGY PRINCIPLES OF THE EVOLUTION OF CONGENITAL DISORDERS BY SYSTEM

EMBRYOLOGY PRINCIPLES OF THE EVOLUTION OF CONGENITAL DISORDERS BY SYSTEM

Lesson Code: MP2003

Professor in charge: Sotiriou Sotiris, Associate Professor

Other Teachers:

ECTS: 2.00

Type|Type of Course: OP | SCIENTIFIC AREA

Teaching Semester: 14th Semester

Hours per week: 2 hours

Total Time (Teaching Hours + Student Workload) 54 Hours

Prerequisites: NO

Language of Instruction: GREEK

Available for Erasmus: OXI

Semester Lectures: Coming Soon…

Teaching Method: Face to face and specifically:
Teaching through life (auditorium lectures/laboratory exercises in a laboratory room) or remote due to special circumstances (COVID-19)
Exams: Written (live in an auditorium – remotely due to special circumstances) The content of the lectures is described above. The attendance of Laboratory Practices and Seminars/Tutorials is mandatory. Information and Communication Technologies are used to prepare the lecture material, the electronic update and the provision of supplementary educational material to students.
ESPECIALLY:
• Common software (eg MS powerpoint) is used to prepare lecture material and display slides and videos.
• The study guide (detailed supplementary material & additional bibliography), the educational material (clinical cases), the theory and protocols of laboratory exercises, the slides of each lecture as well as relevant videos and scientific articles available electronically and online to students through e-class system of our university.
• Information about the course, the lecturers and their research interests and the Histology and Embryology department of the School of Medicine in general is available online on the School of Medicine website
• Common software (eg MS excel) is used for the statistical processing of student evaluation.
Announcements, information, etc. are available online through e-class. Communication is also done via e-mail (embryology-histologylab@uth.gr).

Evaluation Method: The evaluation language is Greek.
Evaluation methods.
A. In laboratory exercises: Mid-semester written test with 7 questions and problem solving.
Student participation in laboratory exercises is mandatory. Successful participation in the practical is certified by the instructors' signatures on the written reports. examination.
B. In the Tutorials: Oral Presentation, Oral Examination
In each tutorial, students prepare answers to the questions related to the examined clinical cases and discuss them with the teachers. Student performance during tutorials is taken into account in the final assessment. Tutorial material is reviewed along with the lecture.
C. In theory – lecture material:: Written Exams with multiple choice questions.
The course exams are written, last 2 hours and consist of multiple choice questions. The material to be examined is lectures and training material as described above.
Final grade:
The final grade of the course is calculated as the sum of the grade of the written exams of the course and the grade of the Laboratory written exams.

Objective Objectives/Desired Results: Human embryonic development is regulated through cascading gene expression.
Human embryos develop their complex histological features through progressive transformation of simpler precursor forms. This particular developmental process is called epigenesis. The epigenetic development of the human embryo is regulated through cascading expression of genes that in turn induce the expression of other genes – a continuous chain of expression – leading to the correct eventual establishment of the characteristics of the human embryo. In case of failure, change of direction, excessive or defective response, the protests of the instruments arise, each of which is explained by the stage where the deviation occurred.
The course can be an essential tool in the undergraduate curriculum for students to understand the key changes that occur early in life that can lead to congenital disorders, the knowledge of which is useful and linked to all basic Medical Specialties.
The course material aims to fully understand the disorder of the principles of Embryology, and Organogenesis that lead to the genesis of congenital disorders, and to introduce students to the basic clinical concepts of congenital disorder of the development of the structures of the human body.
It also refers to the concept of students' acquisition of inductive thinking, which is considered necessary for the proper initiation of students into the function of the Doctor.
Finally, the aim of the course is the students' understanding of the importance of epigenetic disorder and its mechanisms.

Upon successful completion of the course, the student will be able to:
• Has understanding and knowledge of the basic principles of epigenesis in Embryology, and Organogenesis, as well as knowing the individual mechanisms that lead to the main congenital anomalies.
• It is able to distinguish differences in epigenetic cascade expression by system.
• To use the terms correctly.
• to organize, analyze and correctly present the induction (principle of creation of the tissues of the human body) and their maturation into the final structures-tissues of the human body knows the pathophysiology and explains embryologically the congenital disorders of the constitution.
• Can collaborate with his/her fellow students to write papers and conduct basic research for presentation at student conferences.

General Skills

The optional compulsory course "EMBRYOLOGY PRINCIPLES OF THE EVOLUTION OF CONGENITAL DISORDERS BY SYSTEM" has as its main objectives:
 The promotion of knowledge and medical ethics, with rules of ethics, which will serve the modern needs of the student - future doctor as well as the needs of society.
 The promotion of knowledge and research, within a free academic environment, aiming at the highest quality educational level.
 The conduct of high-level research, which will be published in modern Medical Journals with a recognized research project and will be recognized internationally.
 The education of male and female students so that they understand the modern form of Medical thought, the way of approaching the patient and the physiology and pathophysiology of various diseases, the way of conducting research, the theories and methodological approaches related to modern Embryology and the methods of studying the embryo in its various stages of development.
 The expansion of collaborations at the educational and research level with other educational and research departments-institutions of the country and abroad, with the aim of updating the way of teaching and Medical research.
 Ensuring guarantees that teaching staff have the ability to teach and conduct research.
Finally, we aim at the proper preparation of male and female students, capable of further proper continuation of their studies within our University as well as their successful careers in the difficult arena of their working life


Course URL : http://eclass.uth.gr/

Course Description: – The genetic regulation of the formation, proliferation, migration and development of primordial germline – gene targeting therapy of inherited diseases
– Imprinting the genome – transmission of congenital diseases
– Cascading expression gene mutations during gastritis and related congenital diseases
– Embryological complaints of abnormal expression of Hox-genes
– Embryological principles of the development of congenital disorders of the heart and vessels.
– Embryological principles of the development of congenital disorders of the gastrointestinal system.
– Embryological principles of the development of congenital complaints by system of the urinary system
– Embryological principles of the development of congenital disorders of the genital system
– Embryological principles of the development of congenital malformations of the limbs
– Embryological principles of the development of congenital malformations by system of the brain and nervous system
A. Student practice in embryological digital atlases
(Professor S. Sotiriou)
B. Demonstration of congenital anomalies in ultrasound examination of fetuses. (Professor S. Sotiriou)

Recommended reading: A. COURSE THEORY
Recommended books:
• Basic principles of Embryology, organogenesis and anatomy
Edition: 1st/2023, Sotiriou Sotirios, Type: Edition, Owner (Publisher): KOSTAKIS DIM. ATHANASIOS
• Human Embryology-From Conception to Birth-Clinical Approach. Type: Paperback, Author: Moore Keith, Issue: 1/2019, BROKEN HILL PUBLISHERS LTD
Other writings:
……..
B. LABORATORIES
……..
Related scientific journals:
…….

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