HEREDITARY CANCER

HEREDITARY CANCER

HEREDITARY CANCER

Lesson Code: PTH0701

Professor in charge: Emmanuel Saloustros, Associate Professor

Other Teachers: Athanasios Kotsakis, Filippos Koinis and guest speakers

ECTS: 2.00

Type|Type of Course: OP | SCIENTIFIC AREA

Teaching Semester: 14th Semester

Hours per week: 2 hours

Total Time (Teaching Hours + Student Workload) 54 Hours

Prerequisites: NO

Language of Instruction: Greek/English (if Erasmus+ students choose the class)

Available for Erasmus: NO

Semester Lectures: Coming Soon…

Teaching Method:

Lectures, patient case discussions and clinical practice in the office.

MS Power point.


Evaluation Method: Multiple choice questions.

Objective Objectives/Desired Results: The purpose of the course is to introduce students to its basic principles clinical treatment of familial and hereditary cancer. Specifically, students will be taught basic principles of human genetics and genetic counseling. The basic principles of cancer genetics and heredity will be presented and the most common syndromes predisposing to the development of cancer will be discussed. Also, students will be taught the basic principles of risk management for people with cancer and their healthy relatives, but also how to manage the psychological impact that a diagnosis of a syndrome that predisposes to cancer can have.

Upon successful completion of the course, the student will be able to:

  • knows the molecular basis of the syndromes that predispose to cancer.
  • knows basic principles of genetic epidemiology and genetic analysis technologies.
  • obtain a complete personal and family cancer history and draw the family tree.
  • knows the main syndromes that predispose to solid and pediatric cancers and the genes that should be examined according to individual and family history.
  • knows basic principles of genetic counseling for syndromes that predispose to cancer.
  • knows about cancer screening tests and their limitations.
  • suggests the basic interventions to manage the increased risk, based on the result of the genetic test.
  • to recognize the different treatment options for patients with hereditary cancer.

Course URL :

Course Description: 1. Principles of human genetics, methods of genetic analysis (2 hours)
2. Principles of genetic epidemiology and cancer screening (2 hours)
3. Principles of cancer genetic counseling (2 hours).
4. Familial and hereditary ovarian breast cancer: management of increased risk (2 hours).
5. Therapeutic treatment of hereditary breast & ovarian cancer (2 hours)
6. Clinical approach to polyposis and hereditary stomach cancer (2 hours).
7. Lynch syndrome: diagnosis, prevention and treatment (2 hours).
8. Management and treatment of hereditary pancreatic cancer and melanoma (2 hours).
9. Therapeutic approaches to patients with hereditary urinary tract cancer syndromes (2 hours).
10. Endocrine neoplasia syndromes (2 hours).
11. Pediatric cancer syndromes (2 hours).
12. Clinical exercise I (2 hours).
13. Clinical exercise II (2 hours).

Recommended reading: Students will be provided with notes, journal articles and presentation slides.

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