| Objective Objectives/Desired Results: | The course is a key tool in the undergraduate courses of the curriculum for medical students to understand the basic principles for the beginning of life, which is the subject of Embryology. The course aims to fully understand all the basic principles of Embryology and to introduce students to the basic concepts of the early stages of development of the human fetus, as well as the molecular events that govern the first stages of development. It also refers to the concept of acquiring inductive thinking in students that are considered necessary for their proper initiation into their medical profession. From this point of view, the course is the basis on which the student will be able to understand and get in touch with other courses of the curriculum (anatomy, histology, basic anatomical and embryological principles of all pre-clinical and clinical special courses). Finally, the aim of the course is to understand the importance of General Developmental Embryology and Molecular Embryology in the context of understanding Clinical Embryology and Assisted Reproduction Embryology. Upon successful completion of the course, the student will: - Have understood the basic principles of Embryology and Molecular Embryology.
- Have knowledge of the course material.
- Be able to distinguish embryos and their structures in the various weeks of early developmental life.
- Use the terms correctly and will combine basic knowledge with the basic principles of related courses such as Histology.
- Analyzes and presents correctly the induction (principle of creation of the tissues of the human body) and their maturation in the final structures – tissues of the human body.
- Collaborate with fellow students to write assignments and perform basic research to be presented at student conferences.
General Abilities - Within the framework of the course and the embryology laboratory, post-graduate courses, workshops, and scientific meetings with active participation in research and inter-university conferences will be organized, aiming at:
- The promotion of knowledge and medical ethics, in combination with the deontology rules will serve the current needs of the student-future doctor as well as the needs of society.
- The promotion of knowledge and research, in a free academic environment, aiming at the highest quality educational level, in order to meet the needs of the medical profession, the needs of the future doctor, and society.
- Conducting high-quality research, published in high-impact factor medical journals.
- To educate students so they understand the modern form of medical thinking, the way of approaching the patient and the physiology and pathophysiology and origin of various diseases, the way of conducting research, the theories and methodological approaches related to modern Embryology and the methods of studying the embryo in its various stages of development.
- The expansion of educational and research collaborations with other educational and research departments – institutions in Greece and abroad, in order to update the way of teaching and medical research.
- To ensure that the teaching staff has the capacity for teaching and conducting research.
Finally, the course aims at the proper preparation of students to be capable of further proper continuation of their studies within the university and their successful career in the difficult field of their working life. |
| Course Description: | SECTION 1 Introduction in embryology – introductory concepts, an overview of embryogenesis, ovulation, spermatogenesis, oocytes, spermatozoa, gamete morphology, acrosomal reaction, fertilization, fertilization factors, zygote formation SECTION 2 Embryonic growth factors, methylation cycle, embryonic development, 2-8 blastomeres, morula, blastocyst, morphology, implantation, implantation factors, abnormal implantation. SECTION 3 2nd week of embryonic development, bilaminar disc, epiblast, hypoblast, gastridiosis, endoderm, mesoderm, ectoderm, trilaminar disc, primary groove, Hensen’s node, neuridiosis, placental formation, villi, umbilical cord, formation of the prechordal plate, oropharyngeal and amacrine membranes, myotomes, dermatomes, formation of embryonic cavities, completion of 3rd and 4th week of development. SECTION 4 Molecular events of fertilization, embryonic development, implantation, gamete and embryo methylation, epigenetic, signal transduction pathways, morphogenesis, abnormalities due to molecular pathway dysfunctions SECTION 5 Gamete processing, Embryonic development in the laboratory, time-lapse monitoring, ICSI/IVF, culture media, morphology and evaluation of gametes and embryos, cryopreservation of gametes and embryos, techniques, pre – implantation genetic diagnosis (PGD), artificial intelligence Laboratory exercises: - Sperm analysis
- Microscopic observation of eggs and gametes.
- Practicing students with placenta preparations at the Museum of Embryology.
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English 
Greek