LECTURES Power point

The general purpose of the course is to introduce students to the basic knowledge of autoimmune diseases and to enable them to plan, analyze and write assessments. Furthermore, the course seeks to provide students with the basics of applied clinical immunology knowledge. The specific objectives of the course are specialized in the following intended learning outcomes:

Upon successful completion of the course the student will be able to use the acquired knowledge in order to:

Understand complex  pathophysiological mechanisms related to the function of the autoimmune system

• write assignments individually or in collaboration with other members (students, small groups)
• make use of bibliography search tools
• have the resources to pursue a future career in specialties that include basic and applied clinical immunology and translational autoimmunity
• organize the way of thinking for the understanding of the immune system and immunopathology
• to approach with critical thinking disorders of the immune system
• collaborate with his fellow students to produce research work

1. Introduction to Immunology
2. Immune system disorders – Autoimmunity
3. Self-reactive immune responses
4. Genetic, Epigenetic and Environmental Mechanisms of Induction of Autoimmunity
5. Regulatory lymphocytes –Th17
6. Autoantigens – Autoantibodies
7. Counting of autoantibodies – Classical Methods (
8. Counting of autoantibodies – New technologies
9. Diagnostic approach of autoimmune diseases
10. Epidemiology of autoimmune diseases
11. Diagnostic criteria – Applications
12. Diagnostic Algorithms
13. Non-organ autoimmune diseases / Pathogenesis, Clinical practice – Therapeutic Options
14. Organ-specific autoimmune diseases / Pathogenesis, Clinical practice – Therapeutic Options
15. Experimental Models of Autoimmune Diseases
16. Treatments – Antidepressants. Steroids – Action, Clinical Applications, Side Effects
17. Treatments – Antidepressants. Immunomodulators of the Disease / Action, Clinical Applications, Side Effects
18. Treatments – Antidepressants. Monoclonal Antibodies and Other Biologic Therapies Immunomodulators of the Disease / Action, Clinical Applications, Side Effects

1.  Instructor Notes
2. Clinical Immunology, Papakosta Despina, Garyfallos Alexandros and associates
3. Basic principles and clinical approach, Boura Panagiota and Associates
4. Carlo Perricone, Yehuda Shoenfeld , Mosaic of Autoimmunity, The Novel Factors of Autoimmune Diseases Revisited, , Elsevier 2019 

Περιοδικά

1. Journal of Autoimmunity,
2. Autoimmunity Reviews
3. Clinical Immunology
4. Nature Immunology,
5. New England Medical Journal
6. Lancet
7. Mediterranean Journal of Rheumatology
8. Annals of Rheumatic Diseases
9. Arthritis and Rheumatology
10. Nature Reviews of Rheumatology