EMBRYOLOGICAL SYSTEMIC DEVELOPMENTAL PRINCIPALS OF CONGENITAL DISORDERS

EMBRYOLOGY PRINCIPLES OF THE EVOLUTION OF CONGENITAL DISORDERS BY SYSTEM

EMBRYOLOGICAL SYSTEMIC DEVELOPMENTAL PRINCIPALS OF CONGENITAL DISORDERS 

COURSE CODEMP2003

COURSE INSTRUCTORSOTIRIOS SOTIRIOU, ASSOCIATE PROFESSOR

CO-INSTRUCTORS 

ECTS:2.00

COURSE TYPE

EL | SCIENTIFIC AREA

TEACHING SEMESTER14st SEMESTER

WEEKLY TEACHING HOURS: 2 HOURS

Total Time (Teaching Hours + Student Workload)54 HOURS

PREREQUIRED COURSES:

NO

LANGUAGE OF TEACHING AND EXAMSGREEK

AVAILABLE TO ERASMUS STUDENTSNO

SEMESTER LECTURES:DETAILS/LECTURES

TEACHING AND LEARNING METHODS :

Face to Face:
Teaching through life (lectures in an auditorium/laboratory exercises in a Laboratory room) or
remote due to special circumstances (COVID-19)
Exams: Written (live in an auditorium – from distance due to special circumstances)
Attendance of Laboratory Practical and Seminars/Tutorials is obligatory.
The lectures content is described above.

Attending Laboratory Practices and Seminars/Tutorials is
mandatory

Information and Communication Technologies are used for the preparation of the lecture material, the online information and provision of supplementary learning material to students.
Specifically:

• Use of information and communication technologies in
teaching (PowerPoint, MS-Teams platform and support learning process through the online platform eClass), laboratory training (interactive method with using electronic programs such asembryodynamics.com) and exams (online written using of the Office 365 platform – MS-Forms).
Common software (e.g. MS PowerPoint) is used to prepare
lecture material and display slides and videos.
• The study guide (detailed supplementary material & additional bibliography), the tutorial material (clinical cases), the theory and protocols of the laboratory exercises, the slides of each lecture as well as relevant videos and scientific articles made available electronically and online to students through the e-class system of our university.
• Information about the course, instructors and their research
interests and in general of Medicine are available online on the
Faculty of Medicine website

Announcements, information etc are available online via e-class.
Communication is also done via e-mail (embryologyhistologylab@uth.gr).


STUDENT EVALUATIONThe language of assessment is English.
Evaluation methods.
A. For the laboratory practical: Written test in the middle of the semester with 7 questions and problem solving.
The participation of students in the laboratory exercises is
mandatory. Successful participation in the practical is certified by the instructors’ signatures on the written reports. exams.
B. For the Tutorials: Oral Presentation, Oral Examination
In each tutorial, students prepare answers to the questions related
to the examined clinical cases and discuss them with the teachers.
The performance of the students during in the tutorials is taken into account in the final evaluation. The material of the tutorials is examined together with the lecture.
C. For the lecture material: Written Exams with multiple choice questions.
The course exams are written, last 2 hours and consist of multiple choice questions. The material to be examined is lectures and tutorial material as described above.
Final Grade:
The final grade of the course is calculated as the sum of the grade of the written course exams and the grade of the Laboratory written exams.
All of the above are presented in detail in the Course Guide which is posted electronically in e-class.

Objective Objectives/Desired Results:

Aims of the course
Human embryonic development is regulated through cascading gene expression. 
Human embryos develop their complex histological features through of progressive change-transformation of simpler precursor forms. The specific development process is called epigenesis. Epigenetic development of the human embryo is regulated through cascading expression of genes which in turn induce the expression of other genes – a continuous chain of expression – leading to the correct eventual creation of its characteristics human embryo. The course can be a basic tool of his undergraduate courses curriculum for students to understand the key changes occurring in principle of life which is possible to lead to developmental disorders , the knowledge of which is
useful and linked to all the main Medical Specialties.
The course material aims to fully understand the disorder of the principles of Embryology, and of Organogenesis that lead to the genesis of congenital disorders, and the introduction of medical
students in the basic clinical concepts of congenital disorder of human body.
It also refers to the concept of acquiring inductive thinking of the students which is necessary for the proper initiation of students to the function of the Doctor.
Finally, the aim of the course is the students’ understanding of the epigenetic mechanisms leading to developmental disordes genesis.
Upon successful completion of the course, the student will be able to:
• Acquire fundamental knowledge of the basic principles of epigenesis in Embryology, and the Organogenesis, as well as knowing the individual mechanisms that lead to the main
congenital anomalies.
• Distinguish differences in epigenetic cascade expression by system.
• Uses terms correctly.
• Analyzes and correctly presents induction (principle of creation of human tissues body) and their maturation in the final structures-tissues of the human body
• Explain the main pathophysiological and embryological mechanisms of congenital malformations.
• Can collaborate with his/her fellow students to write assignments and conducting basic research for presentation at student conferences.

General Abilities

The optional compulsory course “EMBRYOLOGY PRINCIPLES OF THE DEVELOPMENT OF RELATED COMPLAINTS PER SYSTEM” has as its main objectives:
• The promotion of knowledge and medical ethics, with ethical rules, which will serve the modern needs of the student – future doctor as well the needs of society.
• The promotion of knowledge and research, within a free academic environment, aiming at the highest quality educational level.
• Conducting high-level research, which will be published in modern medicine Journals with recognized research work and will be recognized internationally.
• The education of medical students in acquisition of modern form of Medical thinking, the approach to the patient and the understanding of physiology and pathophysiology of the
various diseases
• The introduction in conducting basic research.
• The knowledge of theories and methodological approaches related to modern Embryology and the methods of studying the embryo in its various stages of development.
• The expansion of educational and research collaborations with other educational institutions and research departments-institutions of the country and abroad, with the aim of updating
the way of teaching and Medical research.
• Finally, we aim at the proper preparation of male and female students, capable of further correct continuation of their studies within our University but also their successful careers in
the difficult arena of their working life


Course URL : 

Course Description:The content of the course includes the following major items:
A. The genetic regulation of formation, reproduction, migration and development of primordial genetics – gene targeting for the treatment of inherited diseases -Imprinting the genome –
transmission of congenital diseases
B. Cascading expression gene mutations during gastritis and related congenital diseases
C. Embryological complaints of abnormal expression of Hox-genes
D. Embryological principles of the development of congenital disorders of the heart and vessels.
E. Embryological principles of the development of congenital disorders of the gastrointestinal system.
F. Embryological principles of the development of congenital disorders by urinary system
G. Embryological principles of the development of congenital disorders of the genital system
H. Embryological principles of the development of congenital malformations of the limbs
I. Embryological principles of the development of congenital disorders by system of the brain and the nervous system.
J. Exercises and demonstration of clinical cases based on videos
Laboratory Practical content
Hands-on learning: Acquisition of general and specific practical & clinical skills:
Exercises and demonstration of clinical cases based on videos
Interpretation of ultrasound images
Resolving practical problems
Operating basic ultrasound equipment
Working as a team
Following instructions
Following safety regulations
Clinical significance of ultrasound images
 
Recommended reading:

Α. Lecture Material
Main suggested textbooks:
1. Basic principles of Embryology, organogenesis and anatomy, Edition: 1st/2023, Sotiriou Sotirios, Type: Edition, Owner (Publisher): KOSTAKIS DIM. ATHANASIOS
2. Human Embryology – From fertilization to Birth-Clinical Orientation, Moore Keith, 1η/2019, BROKEN HILL PUBLISHERS LTD
Further reading:

Β. Laboratory Practical supplementary Material
……..
Relevant Scientific Journals:

 


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